The Ageing Endothelium

in Vascular Biology
View More View Less
  • 1 K Ting, Centre for the Endothelium Vascular Biology Program, Centenary Institute, Sydney, Australia
  • 2 P Coleman, Centre for the Endothelium Vascular Biology Program, Centenary Institute, Sydney, Australia
  • 3 Y Zhao, Centre for the Endothelium Vascular Biology Program, Centenary Institute, Sydney, Australia
  • 4 M Vadas, Centre for the Endothelium Vascular Biology Program, Centenary Institute, Sydney, Australia
  • 5 J Gamble, Centre for the Endothelium Vascular Biology Program, Centenary Institute, Sydney, Australia

Correspondence: Ka Ka Ting, Email: k.ting@centenary.org.au

Cellular senescence is now recognised as one of the hallmarks of ageing. Herein, we examine current findings on senescence of the vascular endothelium and its impacts on age-related vascular diseases. Endothelial senescence can result in systemic metabolic changes, implicating senescence in chronic diseases such as diabetes, obesity and atherosclerosis. Senolytics, drugs that eliminate senescent cells, afford new therapeutic strategies for control of these chronic diseases.

If the inline PDF is not rendering correctly, you can download the PDF file here.

 

Sept 2018 onwards Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 479 479 479
PDF Downloads 13 13 13