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Isabelle Coornaert Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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Annelies Breynaert NatuRAPT Research Group, University of Antwerp, Antwerp, Belgium

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Nina Hermans NatuRAPT Research Group, University of Antwerp, Antwerp, Belgium

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Guido R Y De Meyer Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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Wim Martinet Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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oxidation is therefore crucial in preventing and mitigating atherosclerosis and its associated cardiovascular complications. Vitamin E is a lipophilic antioxidant that includes both tocopherols and tocotrienols. It is found in vegetable oils and nuts. The

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Isabelle Coornaert Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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Annelies Breynaert NatuRAPT Research Group, University of Antwerp, Antwerp, Belgium

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Nina Hermans NatuRAPT Research Group, University of Antwerp, Antwerp, Belgium

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Guido R Y De Meyer Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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Wim Martinet Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium

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lipid antioxidant α-tocopherol (vitamin E) ( 6 , 7 , 8 ). Moreover, systemic deletion of GPX4 in mice causes embryonic lethality ( 6 , 9 ), while overexpression of GPX4 blocks cell death mediated by lipid reactive oxygen species ( 10 ). These data

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Ana Correia-Branco Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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Ariel Mei Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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Sreehari Pillai Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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Nirmala Jayaraman Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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Radhika Sharma Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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Alison G Paquette University of Washington, Department of Pediatrics, Seattle, Washington, USA

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Naveen K Neradugomma Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA

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Ciara Benson Department of Bioengineering, University of Washington, Seattle, Washington, USA

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Nicholas W Chavkin Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA

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Qingcheng Mao Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA

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Mary C Wallingford Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts, USA

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phosphate wasting, refeeding syndrome, ectopic calcification, chronic kidney disease, and bone mineralization disorders. Phosphate homeostasis is regulated by parathyroid hormone (PTH), vitamin D (VD), and fibroblast growth factor 23 (FGF23) in concert with

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Alessandra Magenta Istituto Dermopatico dell’Immacolata, IDI-IRCCS, Rome, Italy

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Reggio Lorde Bristol Medical School (Translational Health Sciences), Bristol Heart Institute, University of Bristol, Bristol, UK

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Sunayana Begum Syed Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA

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Maurizio C Capogrossi Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
Division of Cardiology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA

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Annibale Puca Ageing Unit, IRCCS MultiMedica, Milan, Italy
Department of Medicine, Surgery and Dentistry, ‘Scuola Medica Salernitana’ University of Salerno, Baronissi, Italy

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Paolo Madeddu Bristol Medical School (Translational Health Sciences), Bristol Heart Institute, University of Bristol, Bristol, UK

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family consists of five members (i.e. miRNA-200a, miRNA-200b, miRNA-200c, miRNA-141, and miRNA-429). MiRNA-200 plays a major role in the epigenetic control of tumorigenesis and Epithelial to Mesenchymal transition (EMT) ( 12 ). A negative feedback loop

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Raafat Mohamed School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia
Department of Basic Sciences, College of Dentistry, University of Mosul, Mosul, Iraq

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Reearna Janke School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia

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Wanru Guo School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia

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Yingnan Cao Department of Pharmacy, Xinhua College of Sun Yat-sen University, Guangzhou, China

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Ying Zhou School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia

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Wenhua Zheng Faculty of Health Sciences, University of Macau, Taipa, Macau, China

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Hossein Babaahmadi-Rezaei Department of Clinical Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Atherosclerosis Research Center, Ahvaz, Iran

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Suowen Xu Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

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Danielle Kamato School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia
Department of Pharmacy, Xinhua College of Sun Yat-sen University, Guangzhou, China

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Peter J Little School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, Australia
Department of Pharmacy, Xinhua College of Sun Yat-sen University, Guangzhou, China

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daily intake of vitamin E had no beneficial effects on cardiovascular outcomes in high-risk patients ( 120 ). One of potential reasons of antioxidant limitations is the difficulties of targeting precise intracellular signalling pathways which leading to

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