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Tomasz Jadczyk, Guido Caluori, Wojciech Wojakowski, and Zdenek Starek

fate/role of vascular stem cells could boost the efficacy and translation of regenerative and targeted vascular therapies. Figure 1 The scope of nanotechnology and stem cell applications in human vascular diseases. Declaration of

Open access

Jaana Schneider, Marianne Pultar, and Wolfgang Holnthoner

-018-20966-1 ) 17 Holnthoner W Hohenegger K Husa AM Muehleder S Meinl A Peterbauer-Scherb A Redl H . Adipose-derived stem cells induce vascular tube formation of outgrowth endothelial cells in a fibrin matrix . Journal of Tissue Engineering and Regenerative

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Karthik Amudhala Hemanthakumar and Riikka Kivelä

Introduction The heart acts as a muscular pump in the hub of a closed blood vascular system to transport oxygenated blood and nutrients to various organs, and to direct the deoxygenated blood to the right ventricle to be re-oxygenated in the

Open access

Xuechong Hong and Wenduo Gu

. ( https://doi.org/10.1126/science.284.5411.143 ) 2 Gu W Hong X Potter C Qu A Xu Q . Mesenchymal stem cells and vascular regeneration . Microcirculation 2017 24 . ( https://doi.org/10.1111/micc.12324 ) 3 Klein D . Vascular wall

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Ebba Brakenhielm and Vincent Richard

Introduction Over the last 15 years, the use of anti-angiogenic agents to inhibit blood vessel growth has clearly established its ‘raison d’être’ in the treatment of human diseases, including multiple types of cancer, but also vascular

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Ambra Cappelletto and Serena Zacchigna

primitive vascular plexus in a process named vasculogenesis ( 1 ). Angiogenesis is the subsequent sprouting of new vascular tubes from pre-existing vessels in response to soluble factors ( in primis the vascular endothelial growth factor-A, VEGF-A, herein

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T Scott Bowen and Stuart Egginton

, psoriasis, rheumatoid arthritis ( 3 ) (see also Table 1 ). Table 1 Summary of the vascular mitochondrial responses/signals linked to a subsequent angiogenic response and the putative stressors involved. Mitochondrial response

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Makeda Stephenson, Daniel H Reich, and Kenneth R Boheler

deposition. Their results established a potentially efficient patient-specific approach for the use of hiPSC-derived vascular cells in the regeneration of vascular tissues in vivo . A handful of heterotypic eVT examples of iPSC-vSMCs cultured with ECs and

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Linda Alex and Nikolaos G Frangogiannis

Introduction Pericytes are vascular mural cells that are embedded within the microvascular basement membrane, enwrapping capillaries, venules and terminal arterioles ( 1 , 2 , 3 , 4 ). In contrast, larger vessels, such as arteries and veins

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Eleonora Zucchelli, Qasim A Majid, and Gabor Foldes

culture condition is still needed to assess phenotype stability and maintenance of functional properties of hPSC-EC after several passages in culture ( 30 ). Finally, mesenchymal stem cells (MSCs) have shown vascular regeneration properties in vitro and in