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Piotr Kobialka and Mariona Graupera

pathological vessel growth Perturbations in class I PI3K signalling have been linked to aberrant vascular growth including tumour angiogenesis and vascular malformations. The impact of PI3K inhibitors on tumour vessels Angiogenesis is a rate

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Timothy D Le Cras and Elisa Boscolo

). PIK3CA mutations in vascular anomalies While vascular malformations are primarily present at birth, they can also become apparent during childhood, and they persist throughout adulthood. The International Society for the Study of Vascular Anomalies

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Amer Harky, Ka Siu Fan and Ka Hay Fan

fibrillin-1 Multisystemic smooth muscle dysfunction syndrome (27, 28) ACTA2 TAAD Defective α-actin affects aortic SMC function Turner syndrome (22) Partial or complete loss of X chromosome TAAD Congenital cardiac and vascular