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Amer Harky, Ka Siu Fan, and Ka Hay Fan

Introduction Thoracic aortic aneurysms and dissections are highly lethal aortic diseases that can present as emergencies and will require urgent surgical treatment: while the majority of patients with dissection and ruptures will not survive

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Sashini Iddawela, Andrew Ravendren, and Amer Harky

Introduction Thoracic aortic aneurysms and dissections (TAAD) are relatively less common when compared with other cardiovascular diseases, but can result in significant mortality and morbidity if managed inappropriately ( 1 ). Mortality of

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Tomasz Jadczyk, Guido Caluori, Wojciech Wojakowski, and Zdenek Starek

of small tumoral masses that escape resection or conventional therapies. Nanorobots have been indeed proposed to spot brain aneurysm detection ( 23 ) and to repair small vessel via Von Willebrand factor (vWF) sensing ( 24 ). These systems would

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Paolo Madeddu

blood vessels throughout the body become inflamed and can form aneurysms, have been also reported. However, this figure is lower than would be normally expected at this time of year when Kawasaki disease generally peaks ( https

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Jarkko P Hytönen, Olli Leppänen, Jouni Taavitsainen, Petra Korpisalo, Svetlana Laidinen, Kari Alitalo, Jonas Wadström, Tuomas T Rissanen, and Seppo Ylä-Herttuala

abdominal aortic aneurysms . Journal of Vascular Surgery 2011 53 1506 – 1513 . ( https://doi.org/10.1016/j.jvs.2011.02.028 ) 7 Kohler TR Stratton JR Kirkman TR Johansen KH Zierler BK Clowes AW . Conventional versus high

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Makeda Stephenson, Daniel H Reich, and Kenneth R Boheler

(COL3A1) mutations, which often lead to vascular dissections and aneurysms in patients. Since mature collagen fibril formation is extremely difficult to achieve in vitro , modeling of vSMC-ECM interactions with lesion formation is experimentally

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Ka Ka Ting, Paul Coleman, Yang Zhao, Mathew A Vadas, and Jennifer R Gamble

expression and reduced eNOS activity ( 23 ). Further, a higher fraction of ECs from patients with abdominal aortic aneurysm (AAA), another clinical manifestation of atherosclerosis, were positive for Ki67 demonstrating a higher proliferation rate compared to

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Abdallah Al-Mohammad, David G Partridge, Graham Fent, Oliver Watson, Nigel T Lewis, Robert F Storey, Michael Makris, and Timothy J Chico

-19 ( 80 ). This condition appears to overlap with Kawasaki’s disease, a vasculitis of unknown cause that can cause hypotension, cardiac dysfunction and coronary artery aneurysms, which may present with myocardial infarction or rupture ( 81 ). A recent

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Manisha S Patil, Siân P Cartland, and Mary M Kavurma

– 199 . ( https://doi.org/10.1016/j.bbrc.2008.09.095 ) 48 Bumdelger B Kokubo H Kamata R Fujii M Yoshimura K Aoki H Orita Y Ishida T Ohtaki M Nagao M , Osteoprotegerin prevents development of abdominal aortic aneurysms . PLoS ONE

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Raafat Mohamed, Reearna Janke, Wanru Guo, Yingnan Cao, Ying Zhou, Wenhua Zheng, Hossein Babaahmadi-Rezaei, Suowen Xu, Danielle Kamato, and Peter J Little

aneurysms . Clinica Chimica Acta: International Journal of Clinical Chemistry 2017 468 . ( https://doi.org/10.1016/j.cca.2017.03.007 ) 108 Foo NP Lin SH Lee YH Wu MJ Wang YJ . α-Lipoic acid inhibits liver fibrosis through the attenuation