Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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most active isomer of vitamin E in the human diet is α-tocopherol ( 6 ). As an antioxidant, vitamin E is able to inhibit the formation of lipid peroxidation by two different mechanisms. Vitamin E acts as a radical-trapping antioxidant, thereby
Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
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lipid antioxidant α-tocopherol (vitamin E) ( 6 , 7 , 8 ). Moreover, systemic deletion of GPX4 in mice causes embryonic lethality ( 6 , 9 ), while overexpression of GPX4 blocks cell death mediated by lipid reactive oxygen species ( 10 ). These data