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Karthik Amudhala Hemanthakumar Stem cells and Metabolism Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland
Wihuri Research Institute, Helsinki, Finland

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Riikka Kivelä Stem cells and Metabolism Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland
Wihuri Research Institute, Helsinki, Finland

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growth factors, which regulate the growth of new and larger blood vessels ( 23 ). In pathological states, cardiomyocyte hypertrophy is associated with a mismatch between oxygen supply and demand, as the increased cardiomyocyte size is not matched by a

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Sarah Schnabellehner Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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Marle Kraft Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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Hans Schoofs Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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Henrik Ortsäter Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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Taija Mäkinen Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

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the renal medulla ( 5 ), and the remodeled spiral arteries of the placental decidua ( 6 ). Uniquely, these hybrid vasculatures are directly connected to blood vessels and in most cases blood perfused, yet express PROX1, which is considered the master

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Tomasz Jadczyk Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
Interventional Cardiac Electrophysiology Group, International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic

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Guido Caluori Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
Nanobiotechnology, CEITEC-MU, Brno, Czech Republic

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Wojciech Wojakowski Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland

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Zdenek Starek Interventional Cardiac Electrophysiology Group, International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic
First Department of Internal Medicine, Cardioangiology, St. Anne’s University Hospital Brno, Masaryk University, Brno, Czech Republic

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– 570 . ( https://doi.org/10.1177/0278364908097586 ) 24 Trihirun S Achalakul T Kaewkamnerdpong B . Modeling nanorobot control for blood vessel repair: a non-Newtonian blood model . In The 6th 2013 Biomedical Engineering International

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Jarkko P Hytönen A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland

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Olli Leppänen A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland

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Jouni Taavitsainen A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland

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Petra Korpisalo A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland

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Svetlana Laidinen A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland

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Kari Alitalo Molecular/Cancer Biology Laboratory, Biomedicum Helsinki, Helsinki, Finland

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Jonas Wadström Department of Transplantation Surgery, Karolinska Hospital Huddinge, Karolinska Institute, Stockholm, Sweden

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Tuomas T Rissanen Heart Centre, North Karelia Central Hospital, Joensuu, Finland

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Seppo Ylä-Herttuala A.I. Virtanen Institute of Molecular Medicine, University of Eastern Finland, Kuopio, Finland
Gene Therapy Unit, Kuopio University Hospital, Kuopio, Finland
Heart Center, Kuopio University Hospital, Kuopio, Finland

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244 – 254 . 14 Brewster LP Bufallino D Ucuzian A Greisler HP. Growing a living blood vessel: insights for the second hundred years . Biomaterials 2007 28 5028 – 5032 . ( https://doi.org/10.1016/j.biomaterials.2007.07.048 ) 15 Antonova LV

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Makeda Stephenson Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, USA

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Daniel H Reich Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, Maryland, USA

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Kenneth R Boheler Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, USA

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Introduction Vascular smooth muscle cells (vSMCs) develop from cell lineage precursors and progenitors to form a layer of non-striated contractile mural cells located between the tunica media and tunica adventitia of blood vessels which

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Luca Marchetti Theodor Kocher Institute, University of Bern, Bern, Switzerland

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Britta Engelhardt Theodor Kocher Institute, University of Bern, Bern, Switzerland

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cells can reach the CNS via three different entry sites: via CNS parenchymal and leptomeningeal blood vessels and via the choroid plexus ( 6 ). Here we will focus on discussing our current knowledge on immune cell trafficking across CNS parenchymal and

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Wessel S Rodenburg Molecular Cell Biology Lab at Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, the Netherlands

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Jaap D van Buul Molecular Cell Biology Lab at Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, the Netherlands
Leeuwenhoek Centre for Advanced Microscopy, Section Molecular Cytology at Swammerdam Institute for Life Sciences at University of Amsterdam, Amsterdam, the Netherlands

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cells can penetrate a nearby blood vessel wall (intravasation) and are transported through the circulation. While in the circulation, cancer cells are referred to as circulating tumour cells (CTCs). At a distant site, CTCs can get trapped, which often

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Hafsa Khan International Centre for Chemical and Biological Sciences (ICCBS), Pakistan

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Tahira Ghulam Aga Khan University Medical College, Pakistan

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Naseer Ahmed Institute of Basic Medical Sciences, Khyber Medical University, Pakistan

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Muhammad Rafai Babar Aga Khan University Medical College, Pakistan

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Simon DJ Calaminus Hull York Medical School, University of Hull, UK

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Muhammad Zuhair Yusuf Aga Khan University Medical College, Pakistan

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Introduction Cardiovascular disorders (CVD) have a significant impact on global health that results in CVD being the cause of 32% of worldwide mortality ( 1 ). It encompasses conditions that affect the heart and blood vessels of the body, such

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Bernah M Fahning Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo - USP, Brazil

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Simone R Potje Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo - USP, Brazil
Department of Medical Sciences, Minas Gerais State University – UEMG, Brazil

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Tiago D Paula Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo - USP, Brazil

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Marcella D Grando Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo - USP, Brazil

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Lusiane M Bendhack Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto - University of São Paulo - USP, Brazil

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Introduction Hypertension induces changes in the cardiovascular system, particularly in blood vessels, causing endothelial dysfunction ( 1 ). Consequently, a hypercontractile profile arises in vascular smooth muscle cells (VSMC) of renal

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Aurélie Hautefort Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland

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Anna Pfenniger Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
Department of Medical Specializations – Cardiology, University of Geneva, Geneva, Switzerland

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Brenda R Kwak Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
Department of Medical Specializations – Cardiology, University of Geneva, Geneva, Switzerland

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during wound healing or tissue regeneration. During angiogenesis, new capillaries sprout from pre-existing blood vessels to expand the vascular plexus. The primary stimuli are a lack of oxygen and nutrients in the surrounding tissues, which induce the

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